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THC redukuje aktywność części mózgu odpowiedzialnej za ból

Brytyjscy naukowcy przekonują, że marihuana nie zmniejsza bólu, ale pozwala człowiekowi nie zwracać na niego uwagi. Wyniki ich badania opublikowano w czasopiśmie „Pain”.

Badacze z University of Oxford odkryli, że THC, główna substancjapsychoaktywna marihuany, redukuje aktywność części mózgu, odpowiedzialnej za emocjonalny składnik odczuwania bólu, jednak ma mały wpływ na ośrodki rzeczywiście związane z nasileniem nieprzyjemnego wrażenia.

Oznacza to, że ludzie po zażyciu THC nie doświadczają zmniejszenia bólu (jak w przypadku przyjęcia opiatów), lecz zobojętnienia i zdystansowania w stosunku do niego.

W dodatku ulga w cierpieniu nie jest udziałem każdego człowieka w równym stopniu, a niektórzy w ogóle nie reagują na uśmierzające działanie marihuany.

Marihuana wydaje się nie działać jak konwencjonalne środki przeciwbólowe. Niektórzy ludzie reagują naprawdę dobrze, inni wcale lub nawet źle – przyznaje dr Michael Lee, główny badacz.

Naukowcy śledzili reakcje mózgowe u mężczyzn, którym podano placebo lub 15 mg THC w tabletce, a następnie wtarto w nogę jeden z dwóch rodzajów maści: obojętną lub z zawartością kapsaicyny (związku występującego w papryczce chilli), wywołującej pieczenie.

Odkryliśmy, że ludzie po zażyciu THC na ogół nie deklarowali żadnej zmiany dotyczącej siły pieczenia, ale w mniejszym stopniu przejmowali się bólem – podsumowuje Lee.

via: PAP



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